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How To Select The Right Syringe Filter

How to Select the Right Syringe Filter

A syringe filter is a membrane-based product that helps eliminate specific pollutants, such as bacterial contamination from liquid samples. Many laboratories utilize syringe filters to quickly and efficiently filter and clean their equipment. A syringe filter is a disposable cartridge filter that is attached to the syringe’s end for use. These might be connected to Luer locks, albeit not always. Using a cursor is preferred when the window is mounted over a syringe filter. The syringe filter typically comprises a plastic covering layer that serves as a filter. But selecting a useful filter can occasionally be challenging. Here are some significant factors that you must consider while selecting the right Syringe Filter

Why We Need The Right Syringe Filter?

Every analytical method that requires required sample filtration is necessary. Even a small mistake can harm the entire procedure. You can obtain reliable findings and expedite the entire diagnostic or diagnostic procedure by selecting the appropriate syringe filter. It’s crucial to select the proper syringe filter for each diagnostic test. When selecting a syringe filter, there are a few things to remember. Here are a few essential items to consider before selecting a wise choice.

Match Pore Size

There are preferences for hole sizes in a variety of syringe filter types. To make sure that your application works as you expect it to, you must confirm that the hole size is appropriate for it. The most typical hole sizes you’ll come across in your range are shown here, along with illustrations of how they are used in frequent situations. 0.1μm is used for solution sterilization and mycoplasma removal. To reduce germs during solution sterilization, a 0.22 Micron Filter is employed. Particle removal and general filtration are done at 0.45 m; pre-filtration is normally done at >0.45 m.

Select The Most Suitable Filter Material

The syringe filters are constructed from a membrane filter with a plastic casing (usually polypropylene). Every layer has several significant physical and chemical elements that make it suitable for a specific kind of system. 

Filter Diameter

The significance of the material to be filtered determines the width of the syringe filter. If the liquid sample has a large volume, a thorough filter should be used. Syringe filters come in a variety of diameters, including 4mm, 13mm, 17mm, 20mm, 25mm, 30mm, and 33mm. Filters with a diameter of 4 mm are used for samples of less than one milliliter (ml), or filters with a diameter of 30 mm are used for samples of 100 ml or more.

Wettability of the Membrane

It is crucial to determine if the membrane is hydrophilic or hydrophobic. Some molecules are blocked by hydrophilic filters, allowing the water to pass to the membrane. Hydrophilic materials include polyethersulfone (PES), nylon, cellulose acetate (CA), regenerated cellulose (RC), Anopore, glass fiber, and polypropylene.

For some specific acidic samples, hydrophilic filters may not be sufficient. In this case, hydrophilic filters that were previously hydrophobic are pre-installed during the display process. Hydrophilic Polytetrafluoroethylene and hydrophilic PVDF (Polyvinylidene Fluoride) filters changed from hydrophobic to hydrophilic.

Association Classification

Syringe filters obtain with female Luer lock inlets and a male Luer slip platform. And to receive protected and tight sealing, filters can be designed with double Luer lock connections that are a female Luer lock inlet and a male Luer lock opening.


Any laboratory technique must include the appropriate filter selection. And this is the initial step toward accurate diagnosis and objective findings. The precise filter enhances the precision of the experimental results. If the wrong filter is selected, it may introduce impurities and unwanted particles into the test sample, leading to inaccurate findings and conclusions.

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